Which one do want to go to? Chicago or Orlando? I can only speak for myself as it’s a very personal decision to make, but if I could, and actually if I can make it, I’d definitely go to Orlando. It’s a smaller con, and there’s a panel with just the two of them, so maybe just for that, it’s worth it no matter what happens in their personal lives. This is going to be a very rare and precious panel. 
Also, my personal policy lately is that I refuse to give one penny to David Duchovny until Brad and Monique are out. This is my way to not support his relationship with her because it’s gross and to not support Brad because *he*’s gross. So if I can make it to Orlando, I’ll go to the panel and that’s it. I won’t be paying for autographs or photo op. So there’s that. 

My final thought on this is that you shouldn’t forget that going to this kind of event is great because you get to see them live but it’s mostly awesome for the people you get to meet and the interactions with other fans and the friendships you can make. This is probably the best part of a comic con or of any events with David and Gillian, to be honest!

(Sorry I just realize I forgot the first part of your message!)